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[9] [10] The key difference lies in their approach: Trulicity provides an external source of GLP-1 receptor stimulation with additional effects on appetite and gastric emptying, whilst Januvia preserves the body's own incretin hormones by preventing their breakdown

Additionally, research suggests depression and, somewhat ironically, antidepressants are associated with sexual difficulties in both men and women

However, some people wish to increase it further, to the level of 4-5 mg per day

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The study also found: Almost 8 in 10 people on the Wegovy pill lost at least 5 percent of their starting weight, compared with about 3 in 10 taking a placebo pill

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