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At 52 weeks, patients previously treated with tirzepatide maintained 74.7% of prior weight loss with orforglipron versus 49.2% with placebo, while those previously treated with semaglutide maintained 79.3% of prior weight loss with orforglipron versus 37.6% with placebo

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The LDL particle, which averages about 45% cholesterol, is the primary particle for the transport of cholesterol from the liver to other cells of the body

Emmanuelle et al., 2023

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