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& Karplus, P
Retinol primarily accelerates keratinocyte turnover and inhibits MMP activity in the epidermis and at the dermo-epidermal junction
Common timeline: First 12 weeks: Side effects may still occur Weeks 35: Side effects typically resolve After 5 weeks: Medication is mostly cleared Side effects usually disappear If side effects persist beyond this period, medical evaluation may be helpful
Washington, DC: National Academy Press
Improving gut inflammation and microbiome health Because GLP-1 works in the gut, it helps restore a healthier microbiome
The FDA prescribing information notes that tirzepatide can reduce the exposure to oral contraceptives, requiring the use of backup contraception for 4 weeks after initiation and after each dose escalation of tirzepatide
