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For AUC 06h,SNAC,day10 and C max,SNAC,day10 , there was no statistically significant interaction between the effects of water volume and post-dose fasting ( p = 0.609 and p = 0.732, respectively) and no statistically significant change with water volume ( p = 0.396 and p = 0.848, respectively)
Phase 1/2 trial reported no serious adverse events at doses up to 60 mcg/kg (Teichman et al., J Clin Endocrinol Metab 2006)
Front Immunol 13:863234 Arnoult D, Gaume B, Karbowski M, Sharpe JC, Cecconi F, Youle RJ (2003) Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization
No significant intergroup differences were found for this parameter
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