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Different mechanisms, overlapping tissue endpoints hence the frequent combination in research protocols

IGF-1 is a hormone in our body that is structurally very similar to insulin

It is also converted to oestrogen, which becomes more important during menopause as the ovaries shut down

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Reduction of Side Effects Gastrointestinal discomfort, including nausea, vomiting, and diarrhea, is a common side effect of semaglutide

Exaggerated insulin/IGF-1 signaling of Western diet and cancer Increased IIS has been implicated to play an important role in most types of epithelial neoplasia [13, 27]