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The Phase 2 obesity trial published in the New England Journal of Medicine reported substantial weight reduction over 48 weeks, while a separate Phase 2 trial in people with type 2 diabetes evaluated glycemic and body-weight effects

Check out their key takeaways: The Role of GLP-1 in Obesity Treatment GLP-1s have emerged from treatment in Type 2 Diabetes to a frontline treatment for obesity due to their efficacy in promoting significant weight loss

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But almost 1 in 8 adults said that they were taking a GLP-1 drug so as to lose weight or maybe treat another chronic condition as of November 2025, as per a poll from KFF, the health policy research organization