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Passive targeted delivery involves the use of carrier systems that prolong residence time and increase bioavailability, leading to higher therapeutic efficacy
doi: 10.1126/science.adf7044 199 LiZ.WangT.DuS.MiaoZ.ZhaoY.TangY.et al
The current study observed very low Nrf-2 expression in COPD-A, showing no significant decrease after PM exposure
23,24,56,75 In addition, it may reduce NAPQI back to APAP by enhancing the sulfonation pathway of APAP metabolism
Attenuating lipid accumulation may decrease CVDs incidence
Although astrocytes can utilize fatty acids as an alternative energy source, prolonged reliance on lipid oxidation results in oxidative stress and mitochondrial impairment, exacerbating neurodegeneration 82
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