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Neither mechanism directly stimulates insulin secretion in a glucose-independent manner, making the combination inherently safer regarding hypoglycaemia compared to sulphonylureas or insulin

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Tell your healthcare provider if you have any signs or symptoms of a urinary tract infection such as a burning feeling when passing urine, a need to urinate often, the need to urinate right away, pain in the lower part of your stomach (pelvis), or blood in the urine