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Allergic reactions to proprietary preparations of vitamin B12 might be due to substances added to the solutions as preservatives or for other reasons, to impurities from the production, or to the vitamin B12 itself

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This seems logical but creates mechanical forces that literally tear peptide bonds apart

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doi: 10.1007/s00284-020-02053-9 330 TungJMDolovichLRLeeCH

Ma G, Jia H,Li Z, Wang L,Zhang Z,Xiao Y,Liang Z,Li D, Tian X,Wang Y, Liang Y, Niu H