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Olasupo Odunsi, MD, Medical Director Reviewed July 22, 2026 B12 shots are marketed everywhere as a weight loss booster

Adults under 130 lbs may use a 28-30 gauge inch or 25g 5/8 inch needle to get Intramuscular benefit

There is also recent data which suggest that genetic alterations of the receptor by which B12 is transported into nerve tissue and the brain, may lead to a lower B12 uptake

This means it is designed to work in the same way as Vitamin B12 Injection

Those who did not receive enough were associated with a much higher risk for obesity

Many individuals benefit from weekly or bi-weekly treatments to keep their energy levels steady