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Although extremely rare, hydroxocobalamin injections can also cause serious side effects such as a major allergic reaction or irregular heartbeats (palpitations)

Some research suggests that athletes with poor or marginal nutritional status for vitamin B12 may have decreased ability to perform high intensity exercise

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alternative-therapies.com PubMed Selective good angiogenesis, blocks bad angiogenesis (evidence: context dependent rodent preclinical modulation, unvalidated in humans)

The practical consequences are two: the ascorbic acid degrades rapidly, losing its antioxidant and collagen-synthesis signaling value before it can act, and the superoxide generated in the process is a reactive oxygen species that may cause irritation or oxidize other formula components

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