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For testing, animals were anesthetized with ketamine (80 mg/kg) and xylazine (10 mg/kg) via i.p
In photodermatology research, afamelanotide an alpha-MSH analog structurally related to MT-II has been investigated for systemic photoprotection in erythropoietic protoporphyria, with vitamin D status monitoring being an important safety consideration (PMID: 38736212)
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doi: 10.1155/2022/2944156 100 SaundersRMBiddleMAmraniYBrightlingCE
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