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Phentermine works by increasing the release of certain chemicals in the brain that help control appetite
Among them, GLP-1 and GIP (gastric inhibitory polypeptide) are known as incretins, gut-derived hormones that enhance glucose-dependent insulin secretion, playing a pivotal role in maintaining glucose homeostasis and serve as important therapeutic targets for type 2 diabetes and obesity
If nausea is persistent or severe, it is advisable to consult with a healthcare provider
GHRP-6 is a hexapeptide GHS-R1a agonist (MW 873.01 Da) with broader receptor activity that increases GH, cortisol, prolactin, and appetite (ghrelin-like)
Spencer Nadolsky, an obesity-medicine specialist who prescribes these medications clinically every day
Same order of magnitude as statin therapy
