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Metabolic impact of endogenously produced estrogens by adipose tissue in females and males across the lifespan

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Across both trials, tirzepatide led to an average reduction in AHI by 2024 events/hour at 52 weeks [113]

Jastreboff and colleagues (NEJM, 2023) reported substantial body-weight reduction in obesity research populations, and Rosenstock and colleagues (Lancet, 2023) documented glycemic and weight effects in type-2 diabetes research populations