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This seemingly controversial impact of GLP-1RAs on DR may be because most trials focused on microvascular and cardiovascular outcomes rather than DR
Apart from ROS being created as a result of oxidative glucose metabolism, the constant exposure of retinal cells to sunlight and artificial light triggers the production of ROS 16,17 , especially with photosensitizers present, such as retinoids 16,18 , and leads to photo-oxidation 19
Not Anyone looking for clinically proven GLP-1 treatment should look elsewhere
In deze grootschalige, wereldwijde studie wordt onderzocht of retatrutide, naast gewichtsverlies, ook complicaties aan hart en nieren kan helpen voorkomen bij mensen met overgewicht
The not-so-good news
Juhsz and Gullner, 2014)
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