tirzepatide type 2 diabetes Big update in pediatric care 🩺 Mounjaro® (tirzepatide) is now FDA-approved for children ≥10 years old with diabetes as an adjunct to diet and exercise. What this means ⬇️ Tirzepatide benefits obese HFpEF patients

Lets break it down in a way that makes sensewithout the medical jargon

The released inflammatory mediators lead to the upregulation of adhesion molecules such as ICAM-1 on liver sinusoidal endothelial cells (LSECs) and hepatocytes as well as 2 integrins (CD11b/CD18) on neutrophils, which regulate the aggregation of immune cells through the production of mediators and the expression of adhesion molecules that assist neutrophil adhesion and transit within the sinusoids, adhesion to target cells and dependent oxidative stress, leading to hepatocyte death [19,20,21]

Sleep Habits Teenagers need eight to ten hours of uninterrupted sleep

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The following table provides a clinically useful framework

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