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Moreover, mitochondria have a role in the induction of the inflammatory response, including the production of mitochondrial reactive oxygen species(ROS) and the up-regulation of the expression of genes linked to glycolysis-related enzymes, which has also been extensively reported in the CNS in COVID-19 [75]

However, it is crucial to note that further in-depth and systematic investigation is necessary to elucidate the specific mechanisms underpinning these observations [124]