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To offset the damage, helper cells seal off the damaged area by creating blockades of protein that help prevent the spread of bacteria and toxins to the surrounding areas
-glutamyl transpeptidase (GGT), an enzyme critical to the catabolism of GSH and its conjugates, appears to be an important biomarker for xenobiotic exposure, and for increased GSH demand
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In addition, circulating insulin-like growth factor-II (IGF-II), (another high-affinity ligand to IGF-IR), may also compensate for the loss of systemic IGF-I in these animals
, including Clostridium butyricum , produce butyrate, which helps to maintain gut epithelial cells and has anti-inflammatory properties [3235]
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