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Youll also get billed three weeks later

According to NICE Clinical Knowledge Summaries and the British National Formulary (BNF), the recommended treatment regimens are: For patients without neurological involvement : Initial treatment: hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks Maintenance: hydroxocobalamin 1 mg intramuscularly every 3 months for life For patients with neurological involvement : Initial treatment: hydroxocobalamin 1 mg intramuscularly on alternate days until no further improvement Maintenance: hydroxocobalamin 1 mg intramuscularly every 2 months for life If neurological symptoms are present, treatment should be started urgently to prevent irreversible damage

These findings suggest a possible role for both compounds in supporting angiogenic responses in experimental models

Some patients experience mild discomfort at the injection site, temporary flushing or a metallic taste during the infusion

It also seems to have prevented the down-regulation of the IGF-I receptor and possibly inhibited apoptosis