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Apply an ice pack to the area for about 10-20 minutes after the injection

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Pregnancy or planned pregnancy Semaglutide is contraindicated in pregnancy

Patients with: Higher starting BMI (35+) Strong insulin resistance High visceral fat levels Strict nutritional compliance may approach 50 pounds within 68 months

The FDA has approved oral semaglutide for adults with obesity (BMI 30) or overweight adults (BMI 27) who also have at least one weight-related condition, such as: Type 2 diabetes High blood pressure Dyslipidemia Cardiovascular disease risk Dr

Published Phase 2 data (NEJM, 2023) showed retatrutide achieving up to 24.2% body weight reduction over 48 weeks and significant hepatic fat reduction, supporting research into obesity, NAFLD/MASH, and insulin resistance models