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The STEP 1 and SUSTAIN 8 of semaglutide trials found 3940% of weight lost on the GLP-1 drugs was lean mass (YIKES)

Injection sites: Abdomen (at least 2 inches from the navel), outer thigh, or upper arm

Stanley TL, Chen CY, Branch KL, Makimura H, Grinspoon SK

For patients who have struggled to sustain a healthy weight and need hormonal appetite support to do so, semaglutide provides a physician-supervised framework for long-term maintenance

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