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This indicates that GSH is the main reductant responsible for maintaining the ER oxidoreductases in a reduced form, which is necessary for the reduction or isomerization of nonnative disulphide bonds

Di Marco et al., 2022)

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My recommended gut healing protocols are as follows: Remove inflammatory triggers: Gluten, processed seed oils, excess alcohol, NSAIDs Support gut barrier function: L-glutamine (5-20g daily), zinc carnosine (75-150mg twice daily), collagen peptides Optimize the microbiome: High-quality probiotics, fermented foods, prebiotic fiber Address underlying infections: SIBO, candida overgrowth, and parasites if they are present This may take a few months, but the payoff extends far beyond reducing peptide site reactions