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Metabolism 2008;57(4):549-554

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Semaglutide may cause side effects including nausea, vomiting, diarrhea, constipation, or abdominal discomfort

Week 48: Phase 2 Results Kept Building At 48 weeks in the same Phase 2 trial, the least-squares mean body-weight change was 17.1% in the combined 4 mg group, 22.8% in the combined 8 mg group, and 24.2% in the 12 mg group, compared with 2.1% for placebo

Here is a straight answer to who should avoid taking retatrutide, based on what the research and clinical data actually show