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These processes are essential for human brain development because they represent a quality control system that prevents brain contamination with the toxic products of damaged molecules and cellular structures [243]
As comprehensively reviewed, lactate exhibits tissue specificity: in white adipose tissue, it can suppress lipolysis via the GPR81 receptor at high concentrations, yet promote lipolysis and browning via 3-adrenergic receptor and mitochondrial pathways at lower concentrations or under specific conditions such as exercise [149, 150]
In Synechocystis , exposure to gentamicin stimulated GSH synthesis, whereas a gshB mutant was killed by the drug, despite carrying a resistance gene
Glutathione contents of tissues in the aging mouse
Symptom improvements were far more pronounced in the frailest patients, says Pandey
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