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Clin Cancer Res 11:84258430
in Spain, its current prevalence ranges between 2833%11,12 and it is a recognized as a cardiovascular risk factor and increases the mortality in this population.1315 Furthermore, in patients with DM2 and advanced CKD there are limitations in the prescription of certain antihyperglycemic drugs (e.g., metformin or sulfonylureas) and there is an increased risk of hypoglycemia with antihyperglycemic treatment,16 a complication that is associated with increased cardiovascular risk17 and hinders the achievement of glycemic control targets
doi:10.1016/j.diii.2013.03.010
They have each gone through rigorous rounds of research and testing for safety and effectiveness and earned FDA approval
As glucose is the primary energy source for the body (and your brain in particular), hypoglycemia is a principal concern for diabetes patients
As a result, Regulatory approval would still require successful completion and review of the full clinical and manufacturing package
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