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A recent study found that the ability of metformin to promote GLP-1 secretion was impaired in mice with a gut-specific knockout of the PEN2 gene (Ma et al., 2022)
Many practitioners combine GHK-Cu with one of these for anti-aging and repair protocols
These outcomes reportedly emerged without direct suppression of specific cytokines such as TNF, which implies a more regulatory character
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doi: 10.7573/dic.212283 32 CamilleriMLupianez-MerlyC
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