Sperm count A Neubauer hemocytometer (Deep 0.1 mm, LABART, Germany) was used to count the sperms under a light microscope at 40 magnification
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Key features of this combination include: Two complementary mechanisms of glucose reduction Significant HbA1c reduction potential Additional benefits beyond glycaemic control Reduced risk of hypoglycaemia compared to insulin-based regimens (though caution is needed if combined with insulin or sulphonylureas, which may require dose reduction) How GLP-1 Receptor Agonists and SGLT2 Inhibitors Work Together Understanding the distinct pharmacological mechanisms of these two drug classes helps explain why their combination can be effective
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Through systematic analysis of clinical trials, meta-analyses, and emerging evidence from landmark studies like SELECT, this paper evaluates whether GLP-1 agonists represent a transformative breakthrough or an overhyped intervention with significant limitations