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In an observational study of patients denied TKA because of an institutional BMI cutoff, only 19.1% reached a BMI below 40 kg/m 2 within 2 years in the absence of dedicated weight-loss protocols, whereas 53.1% neither underwent TKA nor became eligible during follow-up ( 3 Why anti-obesity pharmacotherapy may change the logic of KOA care Modern anti-obesity pharmacotherapy may change the management of obesity-related KOA by making clinically meaningful weight reduction more achievable for selected patients

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T., Hurwitz, S., Mossey, C

Measured height and weight with dates, a calculated body mass index consistent with the labeled population, diagnosis codes for every weight-related condition, records of prior structured diet and activity interventions and their outcomes, and any relevant laboratory results

Someone on 2.4mg weekly draws only 24 units, a tiny, comfortable injection