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doi:10.1016/j.nut.2019.110700 Gutman JBL, Kongshavn PAL
The free thiol (-SH) group on its cysteine residue donates an electron to neutralise reactive oxygen species (ROS), reactive nitrogen species (RNS), and other free radicals that would otherwise cause oxidative damage to lipids, proteins, and DNA
The decreased expression of G6PD causes reactive oxygen species accumulation and redox imbalance, which ultimately leads to increased apoptosis in podocytes[33]
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