Unfortunately, even in those with T2D for whom trials of GLP-1 RAs have consistently shown benefit and who are recommended for therapy by the American Diabetes Association, uptake of these therapies has been low, the authors wrote
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Multiple reviewers describe 10-20+ lbs lost over 3-6 months
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These alternatives include other GLP-1 agonists like Trulicity and Saxenda, as well as non-GLP-1 medications such as SGLT-2 inhibitors, DPP-4 inhibitors, sulfonylureas, and thiazolidinediones