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Some patients notice initial improvements in mental clarity, focus, or learning capacity within 1-2 weeks as synaptic formation begins
Use a different quadrant of the abdomen, thigh, or upper arm each week
The latter include synaptic protection, improvements in cognition, learning and motor function, amyloid pathology-ameliorating properties (A, Tau, and -synuclein), the suppression of Ca 2+ deregulation and ER stress, potent anti-inflammatory effects, the blockage of oxidative stress, mitochondrial dysfunction and apoptosis pathways, enhancements in the neuronal insulin sensitivity and energy metabolism, functional improvements in autophagy and mitophagy, elevated BDNF and glial cell line-derived neurotrophic factor (GDNF) synthesis as well as neurogenesis
PMCID: PMC3299230
Side effects can include nausea and gastrointestinal symptoms, but these are often temporary and manageable
After 3 months, the group saw a 5.9% reduction in total body weight , and after 6 months, this increased to 10.9%
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