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doi: 10.1089/ars.2012.5149 195 MohammadiH.ShamshirianA.EslamiS.ShamshirianD.EbrahimzadehM
Largest trial reported increased risk and persistence of CIPN with prophylactic use
However, most studies assessing safety issues or toxicity of -tocopherol supplementation have lasted only a few weeks to a few months, and side effects associated with long-term -tocopherol supplementation have not been adequately studied
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