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Predominance of the 1,N2-propano 2-deoxyguanosine adduct among 4-hydroxy-2-nonenal-induced DNA lesions

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It is used in cell cultures and animal assays to investigate extracellular matrix remodeling , vascular signaling , and mucosal defense

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The drug exerts a wide variety of beneficial effects, including reducing blood sugar (glucose), body weight, blood pressure, blood lipids such as cholesterol, and inflammation, any of which can contribute to the reduction in MACE risk