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A trial of cyclosporine at reperfusion in liver transplant showed a trend to less AST release, though not significant

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Growing evidences indicate that the increased production of reactive oxygen species and oxidative stress, a condition occurring when this balance is disrupted by excessive production of reactive oxygen species and/or by inadequate antioxidant defenses, in the brain are among the causative mechanisms of cerebral tissue damage in both ischemic and hemorrhagic strokes