Start with a small test budget, track outcomes objectively, and rotate through a handful of titles to avoid overfitting your expectations to a single result
Oxidative stress (formulated in Harman's free radical theory of aging) is also thought to contribute to the process
Duodenal mucosal resurfacing, an endoscopic procedure in which the duodenal mucosa is removed by infusing warm water, is equally effective in reducing blood glucose and improving insulin sensitivity and secretion within a few months
doi: 10.1016/j.nut.2016.01.023 73
The IL-17 and IL-23 inhibitor classes, including those targeting the IL-17 receptor (brodalumab), IL-17 cytokine antagonists (secukinumab, ixekizumab, bimekizumab), and IL-23 cytokine antagonists (guselkumab, risankizumab, tildrakizumab)
Less common but more serious effects can include pancreatitis, gallbladder issues, and severe nausea that prevents adequate nutrition