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This review provides a brief overview of the physiological importance and highlights the therapeutic potential of the following gut hormones: serotonin, glucose-dependent insulinotropic peptide, glucagon-like peptide 1, oxyntomodulin, peptide YY, insulin-like peptide 5, and ghrelin
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Tirzepatide ( Zepbound / Mounjaro ): In the SURMOUNT-1 trial, participants on the highest dose (15 mg weekly) reportedly lost an average of about 20.9% of body weight over 72 weeks
He has seen some patients who have been on a GLP-1 for a few years lose 20, 30 or even 50-plus pounds, though results vary from patient to patient
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