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10.3 Hypoglycemia (Especially with Insulin or Sulfonylureas) Risk increases when combined with other glucose-lowering agents
Although speculative, we assume that after short exposure of artery to hyperglycemia and/or hypercholesterolemia, GLP-1 receptor increases to protect artery initially, but that after chronic exposure to them, such protective pathway does not appropriately function
Weekly injectables: Wegovy (semaglutide) and Mounjaro (tirzepatide) Guidance: educational content, Q&A sessions with prescribing pharmacists, and a private community for patients Daily oral tablet formats are also mentioned on myBMIs site, though they arent listed in active treatment plans
Other exclusion criteria were treatment with an SGLT-2I, GLP-1RA or dipeptidyl-peptidase 4 inhibitor (DPP4-I) within 30 days before randomisation, a cardio- or cerebrovascular event within the last 90 days or planned revascularisation
