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Patients included in the trial had HbA1c 7-10% and were treated with either diet and exercise alone, or any oral anti-hyperglycemic agent except dipeptidyl peptidase-4 (DPP-4) inhibitors or GLP-1 receptor agonists

doi: 10.1023/b:bebm.0000035139.31138.bf

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AMG-232 was approved by the FDA following this trial

In fact, because it lowers immune defenses, taking it can sometimes increase your risk of developing an infection

In the study, 32 patients between the ages of 34 and 54 and without diabetes were given 1,000 milligrams of Acetyl-L-Carnitine twice daily for 6 months