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These structural modifications result in approximately 98% albumin binding in physiological buffers and an extended plasma half-life compared to unmodified GLP-1 analogs in preclinical pharmacokinetic studies

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The drug follows a two-compartment pharmacokinetic model with first-order absorption and elimination, meaning it distributes between the blood and tissue compartments at predictable rates

First, we tested the levels of neurotoxic aggregating proteins

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