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doi: 10.1016/j.cmet.2022.07.013 80 le RouxCWSteenOLucasKJStartsevaEUnseldAHennigeAM

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It binds to a protein on multiple myeloma cancer cells called cereblon, resulting in the cells death

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The pigment deposition results in a characteristic dark brown to black discoloration of the lining of the large intestine

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They should also be used cautiously in patients with a history of pancreatitis or gastroparesis

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