Herling M, Khoury JD, Washington LT, Duvic M, Keating MJ, Jones D
Important safety considerations include the risk of acute pancreatitis (seek urgent medical attention for severe, persistent abdominal pain), gallbladder disease, and potential worsening of diabetic retinopathy, particularly in patients with pre-existing retinopathy who experience rapid improvement in blood glucose control
Presented for research literature review only Tew KD et al
Dean JV, Devarenne TP, Lee I-S, Orlofsky LE 1995 Properties of a maize glutathione S-transferase that conjugates coumaric acid and other phenylpropanoids
HOW MOTS-C PEPTIDE REGULATES GLUCOSE Clinical studies have shown that MOTS-c promotes the production of endogen AMP analogue AICAR, which in turn, helps in the synthesis of AMP-activated protein kinase [1] (also referred to as AMPK)
increases the expression of Claudin-1, ZO-1 and Occludin