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This slow titration helps your body adjust and minimises side effects: 6 Weeks 1-4: 0.25 mg once weekly Weeks 5-8: 0.5 mg once weekly Weeks 9-12: 1.0 mg once weekly Weeks 13-16: 1.7 mg once weekly Week 17 onwards: 2.4 mg once weekly (maintenance dose) Practical tips for taking both medications Inject Wegovy on the same day each week, at any time of day, with or without food Continue taking metformin with meals as prescribed Stay well hydrated, especially if experiencing gastrointestinal side effects Eat smaller, more frequent meals if nausea is troublesome Limit ultra-processed food and take-aways Who should not combine Wegovy and metformin

Miralax (Polyethylene Glycol 3350) is highly recommended for GLP-1 constipation because it is an osmotic laxative

Symptoms get better as people develop stable habits with meals, water intake, and sleep

We grew up loving ice cream but want a healthier option without compromise

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Clear to slightly opalescent solutions are normal for standalone tirzepatide