By the end of the 1960s it was clear that there were a number of peptide substances with similar biological properties to glucagon present along the entire length of the intestine, from the duodenum to the rectum
Furthermore, post hoc subgroup analyses of cardiovascular outcome trials have suggested a greater cardiorenal protection in patients treated with a combination versus either monotherapy
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Res Rev Biomed Biotech 1(2):8389 Kiani AK, Pheby D, Henehan G, Brown R, Sieving P, Sykora P, Marks R, Falsini B, Capodicasa N, Miertus S (2022) Ethical considerations regarding animal experimentation
however, these variants, which had a low predicted pathogenicity, were common in patients with different underlying liver diseases
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