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IL-10 is an immune regulatory factor involved in antigen presentation, which can inhibit the production of pro-inflammatory cytokines IL-1, IL-6, IL-8, and TNF- [269, 275,276,277,278,279], and has potent anti-inflammatory effects [280]

The SELECT trial builds on these results, showing that once-weekly semaglutide resulted in a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in patients with pre-existing cardiovascular disease and BMI 27kg/m 2

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J.MulpuriY.LeggioL.SpigelmanI

Nutrients 13

"Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks"