Chronic excess appetite the kind that drives obesity is typically rooted in a combination of gut microbiome disruption (which directly reduces natural GLP-1 production), poor sleep (which elevates ghrelin and suppresses leptin), chronic psychological stress (which elevates cortisol and drives hedonic eating), ultra-processed food consumption (which bypasses the satiety systems normal braking mechanisms), and Agni dysfunction in Ayurvedic terms the digestive fire that governs how food is metabolised and whether it nourishes or accumulates
Amino Acids
Heart failure with preserved ejection fraction for the clinician highlights from the 5th annual Charleston HFpEF conference
ICARUS-Lung01 is a multicentre, single-arm, phase II trial evaluating Dato-DXd in refractory NSCLC (including patients with an actionable genomic alteration) and progressing to at least one line of immunotherapy and platinum-doublet regimen
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