glp-1/gip agonists Understand Dual Agonist Tirzepatide and Its Effect on Current Weight Loss Therapy Science Behind GLP 1 GIP

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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

Springer Link , Journal of Nutrigenetics and Nutrigenomics , vol

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