Gastroenterology Research and Practice, 2015 , Article 387891
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There is a synthetic version which doctors can prescribe, but which can cause liver damage, serious psychiatric effects and heart and respiratory problems if taken without medical oversight
This changed with new American regulations, limiting the selling of injectables and needles without a prescription from a physician
But a better choice is combining adenosylcobalamin and hydroxocobalamin, a precursor of vitamin B12 that benefits the myelin nerve sheath and supports mitochondrial health
While the mechanistic data for how LDN and these specific peptides work is strong and growing, large-scale, double-blind clinical trials for their combined use in Hashimotos are still lacking