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For instance, declining gait speed, physical function and cognition, mitochondrial aging, elevated inflammation, immune dysfunction, frailty and other health conditions are significantly higher in people with HIV when compared to age- and sex-matched uninfected people

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Sepsis-induced metabolic reprogramming drives increased lactate accumulation and systemic oxidative stress, triggering multiple cell death pathways in both immune and parenchymal cells (82,104)

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

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