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The main players in the appetite control pathway are the intestinal hormones produced by the EECs, the VN, the hypothalamus, and the brainstem
The FDA-approved criteria for semaglutide (Wegovy) include adults with a BMI of 30 or greater (obesity), or adults with a BMI of 27 or greater (overweight) who have at least one weight-related comorbidity such as type 2 diabetes, high blood pressure, high cholesterol, or obstructive sleep apnea
Most patients start with regular in-clinic visits to allow for dose adjustments, side effect management, and progress tracking
GLP-1s are approved by the Food and Drug Administration (FDA) for chronic weight management and Type 2 diabetes
C.WangZ.ChoA.et al
Jones BG, Rose FA, and Tudball N (1994)
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