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Raun and colleagues (Eur J Endocrinol, 1998) characterised it as the first growth hormone releasing peptide with selectivity approaching that of GHRH itself, reporting growth hormone release without the accompanying ACTH and cortisol elevation seen with earlier compounds in the class such as GHRP-6 and hexarelin
That same reactivity makes it profoundly unstable when exposed to its enemies: heat, light, and oxygen
On a d'un ct peu d'tudes cliniques srieuses avec des rsultats faiblement significatifs 29
30(2): 3168 De Sousa C, English NR, Stacey TE, et al
Growth Hormone Secretagogues as Potential Therapeutic Agents to Restore Growth Hormone Secretion in Older Subjects to Those Observed in Young Adults
Low GSH levels impair immune response and increase susceptibility to infections
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